Mayo Clinic Scottsdale is at 13400 East Shea Boulevard, Scottsdale, AZ 85259, east of Loop 101. The campus handles outpatient care, research, and medical education. Gated neighborhoods surround it, and Lost Dog Wash Trailhead in the McDowell Sonoran Preserve is a few miles northwest.

Is Mayo Clinic in Scottsdale or Phoenix?

Mayo Clinic has a campus in Scottsdale and Phoenix.

Patients go to the Scottsdale campus on Shea Boulevard for clinic visits, tests, and outpatient surgery. Mayo Clinic Hospital is on the Phoenix campus at 5777 East Mayo Boulevard, Phoenix, AZ 85054, and it has the emergency department.

The two campuses are 14 miles apart. A free Mayo Clinic shuttle runs between them Monday through Friday every half hour from 6 a.m. until 5:30 p.m.

When Did Mayo Clinic Open in Scottsdale?

Mayo Clinic opened its Scottsdale campus in 1987. Its main campus is in Rochester, Minnesota. The Mayo family tie to Arizona goes back to the 1930s, when Drs. William and Charles Mayo spent their winters in the state.

The Mayo Clinic Alix School of Medicine opened its Arizona campus in Scottsdale in 2017.

What Is on the Mayo Clinic Scottsdale Campus?

The Mayo Clinic Building handles diagnostic tests, lab work, outpatient surgery, imaging, and pharmacy services.

Four research and education buildings share the campus:

  • Collaborative Research Building
  • Samuel C. Johnson Research Building
  • Center for Procedural Skills Innovation
  • Arizona campus of the Mayo Clinic Alix School of Medicine

What Is Mayo Clinic in Arizona Known For?

U.S. News & World Report ranked Mayo Clinic No. 1 in Arizona in its 2026-2027 Best Hospitals rankings.

That makes 14 years in a row at the top of the state list.

Approximately 11,000 people work for Mayo Clinic in Arizona, and its transplant center performs more adult solid organ transplants than any other center in the country.

What Homes Are for Sale Near Mayo Clinic Scottsdale?

Homes near Mayo Clinic Scottsdale are in high demand. Townhomes, single-family homes, and custom estates are for sale in gated neighborhoods like Scottsdale Mountain, Sierra Foothills, Sonoran Heights, and The Reserve Scottsdale. 

All four communities share the 85259 ZIP code with Mayo Clinic Scottsdale. 

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Scottsdale Mountain

Scottsdale Mountain is a guard-gated community of custom estates north of Via Linda, near 136th Street. Many homes are on hillsides with city and mountain views. Home gyms, theater rooms, libraries, and offices are common, and some garages keep up to eight cars.

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Sierra Foothills

Sierra Foothills is a gated neighborhood of single-family homes at Shea Boulevard and 128th Street, west of Mayo Clinic Scottsdale. Homes have open floor plans, tile floors, and upgraded kitchens.

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Sonoran Heights

Sonoran Heights is a small gated community of custom homes near Via Linda and 124th Street. Lost Dog Wash Trailhead is near the neighborhood. Homes have vaulted ceilings and open floor plans, and many have pools.

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The Reserve Scottsdale

The Reserve Scottsdale is a small gated community of townhomes at Via Linda and 136th Street. Construction finished in 2022. Floor plans have two bedrooms and a den, or three bedrooms, and some townhomes have private elevators.

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What Restaurants Are Near Mayo Clinic Scottsdale?

There are several restaurants near Mayo Clinic Scottsdale that offer a wide variety of cuisine. Casa Mia serves Italian food on North 136th Street. George & Son's Asian Cuisine has Chinese and pan-Asian dishes on East Via Linda. Farther west on Via Linda, Voila French Bistro is open for dinner.

What Schools Are Near Mayo Clinic Scottsdale?

Scottsdale Unified School District runs the public schools around the campus. Anasazi Elementary School teaches pre-kindergarten through fifth grade at 12121 North 124th Street. Desert Mountain High School is at 12575 East Via Linda.

Are You Searching for a Home Near Mayo Clinic Scottsdale?

The Kay-Grant Group knows the neighborhoods around Mayo Clinic Scottsdale and across the city. Call us at 480-387-3990 or fill out our contact form to get started.

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Published by The Kay-Grant Group, Scottsdale real estate specialists.

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FAQs About Mayo Clinic Scottsdale

What is the address of Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is at 13400 East Shea Boulevard, Scottsdale, AZ 85259.

Is there a Mayo Clinic hospital in Scottsdale?

No. Mayo Clinic Hospital and its emergency department are on the Phoenix campus.

Is there a shuttle between the Scottsdale and Phoenix campuses?

Yes. A free shuttle runs every half hour on weekdays.

Is there a medical school at Mayo Clinic Scottsdale?

Yes. The Mayo Clinic Alix School of Medicine has its Arizona campus there.

Are there gated communities near Mayo Clinic Scottsdale?

Yes. Scottsdale Mountain, Sierra Foothills, Sonoran Heights, and The Reserve Scottsdale are all gated.

Are there hiking trails near Mayo Clinic Scottsdale?

Yes. Lost Dog Wash Trailhead is at 12601 North 124th Street, northwest of the campus.